PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam
نویسندگان
چکیده
Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components confirming the presence of the indole nucleus. Anti-inflammatory activity was carried out on albino rats. Further, anti-inflammatory activity was compared to that of the standard drug indomethacin and percent inhibition of oedema was determined. Sedative hypnotic activity was also evaluated using pentobarbital which showed mild sedation.
منابع مشابه
Anxiolytic and sedative effects of extracts and essential oil from Citrus aurantium L.
Citrus aurantium L. is commonly used as an alternative treatment for insomnia, anxiety and epilepsy. Essential oil from peel (EOP) and hydroethanolic (70% w/v) extract (HE) from leaves were obtained. Hexanic (HF), dichloromethanic (DF) and final aqueous (AF) fractions were obtained from HE by successive partitions. Swiss male mice (35-45 g) were treated orally with 0.5 or 1.0 g/kg of these prep...
متن کاملOtostegia persica (Lamiaceae): A review on its ethnopharmacology, phytochemistry, and pharmacology
Abstract Objective: The current study summarizes the updated information concerning the ethnopharmacology, Phytochemistry, and pharmacology of Otostegia persica Boiss. (Lamiaceae), an endemic medicinal plant in south and southeast of Iran. Materials and Methods: Information was collected through bibliographic investigation from scientific journals, books, theses, reports, and electronic search ...
متن کاملOtostegia persica (Lamiaceae): A review on its ethnopharmacology, phytochemistry, and pharmacology
OBJECTIVE The current study summarizes the updated information concerning the ethnopharmacology, Phytochemistry, and pharmacology of Otostegia persica Boiss. (Lamiaceae), an endemic medicinal plant in south and southeast of Iran. MATERIALS AND METHODS Information was collected through bibliographic investigation from scientific journals, books, theses, reports, and electronic search (database...
متن کاملAvailability, Pharmaceutics, Security, Pharmacokinetics, and Pharmacological Activities of Patchouli Alcohol
Patchouli alcohol (PA), a tricyclic sesquiterpene, is one of the critical bioactive ingredients and is mainly isolated from aerial part of Pogostemon cablin (known as guanghuoxiang in China) belonging to Labiatae. So far, PA has been widely applied in perfume industries. This review was written with the use of reliable information published between 1974 and 2016 from libraries and electronic re...
متن کاملEvaluation of Neuropharmacological Activity of Dioscorea bulbifera Using Various Experimental Models
Dioscorea bulbifera commonly known as Varahikanda, is widely distributed throughout the India, and it has been traditionally used for the treatment of nervous excitability, senility and hysteria. Based on this, neuropharmacological activity of tubers of D. bulbifera was evaluated using various experimental models. Effects of hydroalcoholic extract of Dioscorea bulbifera tubers (DBE) (10,30,100,...
متن کامل